HYTEN
(Risk of High Blood Pressure – Hypertension)
qPCR SNP Detection Kit
Description
NOS3, ACE genes are controlling production of enzymes responsible for lowering and regulating blood pressure. Changes in the indicated genes are associated with a change in the level of the enzyme in the body, which increases the likelihood of fluctuations in blood pressure, the development of cardiovascular diseases and may lead to changes in the structure of blood vessels and the development of atherosclerosis.
REF. NUMBER
755SNP451phb
PREDISPOSITION
Risk of High Blood Pressure (Hypertension)
ANALYSED GENES
NOS3, ACE
IDENTIFIED POLYMORPHISMS
rs2070744, rs4343
KIT CONTENTS
2 × Nuclease-Free Water
2 × 2xSNP MasterMix
2 × Oligos Set
2 × Positive Control Set
QUANTITY
100 rxns
STORAGE CONDITIONS
-25°C to -15°C
CERTIFICATES
More Information
Did you know...?
Hypertension is a disease characterized by periodically or prolonged high blood pressure, i.e. blood pressure of 140/90 mm Hg or more. In general, it is asymptomatic, but in some cases there may be headaches, low energy or sleep disturbances. Occasionally, high blood pressure also causes more serious health problems, such as ventricular hypertrophy, accelerated development of atherosclerosis, impaired kidney function, and stroke.
What are the risk factors?
Factors that influence the risk of developing high blood pressure can be divided into:
- genetic factors, i.e. the genetic profile defined by this study,
- environmental factors, such as excessive salt consumption, smoking, low physical activity, diet rich in fat,
- other factors, such as the influence of hormones, certain drugs, the nervous system, adrenaline levels, other comorbidities such as atherosclerosis or obesity.
How the test is performed?
The NOS3 and ACE genes are DNA fragments that contain instructions for building proteins that are involved in regulating contraction of blood vessel walls. The offered research concerns specific positions in both genes where changes (polymorphisms) may occur. The method used for gene analysis is real-time PCR. The technique used allows for quick and easy identification of the patient’s genetic variant.
How will the client benefit?
The kit we offer contains ready-to-use reagents, which, when added in the right proportions, are ready for reaction. The product IFU included in the kit allows easy interpretation of the obtained data. The client receives a genetic report with a description of his genotype and a detailed explanation and recommendations tailored to his individual genetic profile. Recommendations indicate to the client the further diagnostic path and preventive measures.
Why is it worth doing a genetic test?
Hypertension is a so-called lifestyle disease, the health consequences of which can even lead to death. Thanks to genetic testing, susceptible individuals can start treatment and prevent the development of serious complications. Determining a patient’s genetic predisposition can be useful for physicians to plan treatment strategies. The prevalence of hypertension in society indicates that testing for predisposition to disease will gain popularity.
What can be done after the test result?
In the case of an unfavorable variant of the gene, it is important to follow the recommendations and consult a doctor. It should be remembered that a normal genotype does not exclude the disease. The great potential of genetic testing makes it possible to predict many diseases and gives a chance to take action to improve health.