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IROME 

(Iron Metabolism) 

qPCR SNP Detection Kit

IROME (Iron Metabolism) qPCR SNP Detection Kit

Description

The TMPRSS6 gene plays a key role in maintaining the balance of iron levels in the body. Changes in this gene are the cause of the predisposition to the so-called iron dependant iron deficiency anaemia.

REF. NUMBER

755SNP451pIM

PREDISPOSITION

Iron Metabolism

ANALYSED GENE

TMPRSS6

IDENTIFIED POLYMORPHISM

rs4820268

KIT CONTENTS

1 × Nuclease-Free Water
1 × 2xSNP MasterMix
1 × Oligos Set
1 × Positive Control Set

QUANTITY

100 rxns

STORAGE CONDITIONS

-25°C to -15°C

CERTIFICATES

More Information

Did you know...?

Iron is a biologically important element due to its ability to be an electron donor and acceptor, which is crucial in the course of reduction and oxidation reactions in the cell. The demand for iron and the efficiency of its metabolism are variable and depend on many factors. Although environmental factors may affect iron metabolism disorders, it is estimated that genetic factors may account for 20–30% of the fluctuations of this element in the blood.

Why iron is important?

Iron is involved in the transport of oxygen in the body, contributes to the proper functioning of the immune system and performs numerous other functions. Low iron levels can lead to anemia manifested by tiredness, pale skin, weakness, breathlessness and dizziness.

How the test is performed?

The TMPRSS6 gene is a DNA fragment that contains instructions for building a protein that helps maintain the proper level of iron in the blood. SNP analysis using our reagents is fast and accurate. Thanks to the IFU instructions included in the kit, the technician can easily interpret the results. The reaction lasts about 2 hours, and the temperature-time profile is selected so that the laboratory can analyze several genes simultaneously using one device. Ready-to-use reagents are included in the kit. It is enough for the lab technician to add each of them in the right proportion and the reaction is ready. Quickly, easily and professionally.

Why is it worth doing a genetic test?

Genetic testing of iron metabolism is a very attractive option for people who are looking for the cause of their problems, and blood test results consistently show low iron levels. Anemia is a common disease, and its cause is not always due to a poor diet. With the development of science, new diagnostic methods are possible. Therefore, using RT-PCR, we can quickly and with 100% accuracy determine whether the cause of low iron levels is in the genes.

What can be done after the test result?

A professional approach to the client will inspire their trust and ignite the desire to learn about other genes. Without the need for sequencing, you can access information about many DNA fragments that affect key parameters of our lives.