(COVID-19 Severity Risk Assessment)
qPCR SNP Detection Kit
Changes in the state of several genes related to respiratory failure are analysed. An unfavourable variant increases the risk of a severe course of COVID-19.
COVID-19 Severity Risk Assessment SNP
1 × Nuclease-Free Water
1 × 2xSNP MasterMix
1 × Oligos Set
1 × Positive Control Set
-25°C to -15°C
Did you know...?
Since 2019, the SARS-CoV-2 virus has spread all over the world, causing the COVID-19 pandemic. It is an acute infectious disease of the respiratory system with symptoms such as cough, runny nose, fever, fatigue, sputum production, and even shortness of breath, which when exacerbated, can lead to respiratory failure and death. According to the WHO, the mortality rate of this disease is approx. 1.2%. In cases of severe COVID-19, hospital treatment is inevitable, often with the use of a ventilator.
What are the risk factors for a severe course of COVID-19?
Risk factors that contribute to severe symptoms of viral infection include old age (over 65 years of age), male gender, and comorbidities (hypertension, diabetes, cardiovascular diseases). In addition, severely ill patients have numerous complications, such as visible lung lesions, neurological disorders, and myocarditis. However, there are serious cases of COVID-19 in patients who are not in any of the risk groups. In this case, human genetic characteristics may explain the differences in the severity of COVID-19 symptoms.
How the test is performed?
The single nucleotide polymorphism rs11385942 has been confirmed to be associated with the respiratory failure observed in COVID-19 disease. The real-time PCR method is used for polymorphism analysis. The unfavorable variant of the rs11385942 polymorphism may predispose to the intensification of disease symptoms and a longer recovery period.
How will the client benefit?
The technique used to analyze the studied polymorphisms ensures precise determination of the genotype, and thus the risk of severe course of COVID-19. Thanks to the ready-to-use reagents included in the kit, the preparation of the reaction mixture is quick, easy and does not require significant lab work. Based on the test result and the decision matrix in the product IFU, the client will receive precise information about their gene variant and the implications for their health. The result is also accompanied by recommendations tailored to the client’s genetic profile.
Why is it worth doing a genetic test?
Determining the genetic variant will allow susceptible individuals to take protective measures against viral infection. Awareness of the risk of a severe course of the disease will help to make the decision to vaccinate against COVID-19.
What can be done after the test result?
In the case of an unfavorable variant of the gene, it is important to follow the recommendations and consult a doctor. It should be remembered that a normal genotype does not exclude the severe course of the disease.